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Intrahepatic CD8+ T-lymphocyte response is important for therapy-induced viral clearance in chronic hepatitis B infection

โœ Scribed by Thjon J. Tang; Jaap Kwekkeboom; Shanta Mancham; Rekha S. Binda; Robert A. de Man; Solko W. Schalm; Johannes G. Kusters; Harry L.A. Janssen


Book ID
116650667
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
291 KB
Volume
43
Category
Article
ISSN
0168-8278

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๐Ÿ“œ SIMILAR VOLUMES


Intrahepatic CD8 T-lymphocytes and HBV c
โœ Thjon J. Tang; Robert A. de Man; Johannes G. Kusters; Jaap Kwekkeboom; Wim C.J. ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 170 KB

## Abstract Recognition of HBVโ€infected hepatocytes by CD8 Tโ€lymphocytes is important for viral clearance. Expression of hepatitis B core antigen (HBcAg) in HBVโ€infected hepatocytes can trigger this antiviral Tโ€cell response. The intrahepatic CD8 Tโ€lymphocytes and HBcAg expression were investigated