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Intradomain Disulfide Bonds Impede Formation of the Alternatively Folded State of Antibody Chains

✍ Scribed by Johannes Buchner; Rainer Rudolph; Hauke Lilie

Book ID
117142694
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
197 KB
Volume
318
Category
Article
ISSN
0022-2836

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πŸ“œ SIMILAR VOLUMES

Native disulfide bonds greatly accelerat
Native disulfide bonds greatly accelerate secondary structure formation in the folding of lysozyme
✍ Michel E. Goldberg; Yvonne Guillou πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 512 KB

## Abstract To assess the respective roles of local and long‐range interactions during protein folding, the influence of the native disulfide bonds on the early formation of secondary structure was investigated using continuous‐flow circular dichroism. Within the first 4 ms of folding, lysozyme wit