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Intracytoplasmic immunoglobulin crystals in follicular lymphoma

✍ Scribed by Ryuichi Wada; Yoshihito Ebina; Hidekachi Kurotaki; Soroku Yagihashi

Book ID: 117818655
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 310 KB
Volume: 33
Category: Article
ISSN: 1532-8392
DOI: 10.1053/hupa.2002.129206

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## A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro The functional immunoglobulin (Ig) genes of B lymphocytes undergo somatic mutations during immune responses. These mutations modify the antigen binding site of the immunoglobulins, thereby enhancin