## Abstract Several regulatory mechanisms have been shown to influence the intraosseous circulation. The influence of general hypovolemia on bone circulation and possible regulatory effects were investigated by recording the intraosseous pressure and PO~2~ and PCO~2~ continuously by mass spectromet
Intracompartmental pressure,Po2,Pco2and blood flow in the human skeletal muscle
✍ Scribed by T. Kiær; K. D. Kristensen
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 235 KB
- Volume
- 107
- Category
- Article
- ISSN
- 1434-3916
No coin nor oath required. For personal study only.
✦ Synopsis
Measurement of PO2, PCO2, and blood flow in skeletal muscle could be a supplement to examination in clinical practice. Mass spectrometry was utilized to measure these parameters in the resting anterior tibial muscle of healthy adults. The partial pressures of oxygen and carbon dioxide were 21 +/- 3.6 and 46 +/- 2.5 Torr, respectively. The intracompartmental pressure was 8 +/- 1.1 Torr. The oxygen tension in muscle varied only slightly when arterial partial pressure was increased. The blood flow (tissue perfusion coefficient) estimated by washout of an inert gas was 5.4 +/- 0.8 ml/100 g/min. The results are in accordance with those from animal studies of skeletal muscle. The study demonstrates the feasibility of measuring PO2, PCO2, and blood flow in skeletal muscle by mass spectrometry.
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