𝔖 Bobbio Scriptorium
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Effects of variation in systemic blood pressure on intraosseous pressure, PO2, and PCO2

✍ Scribed by Dr. Thomas Kiær; Jørgen Grønlund; Birgit Jensen; Eiliv Svalastoga

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
409 KB
Volume
8
Category
Article
ISSN
0736-0266

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✦ Synopsis

Abstract

Several regulatory mechanisms have been shown to influence the intraosseous circulation. The influence of general hypovolemia on bone circulation and possible regulatory effects were investigated by recording the intraosseous pressure and PO~2~ and PCO~2~ continuously by mass spectrometry in rabbits. Hypovolemia was induced by repeated bleedings. The intraosseous and arterial pressures were found to be linearly related. The intraosseous PO~2~ already decreased after the first step of bleeding and decreased more than 50% of the initial value after an average blood loss of 40 ml. The intraosseous PCO~2~ showed an opposite pattern. The experimental PO~2~ vs. arterial pressure curves were similar to curves obtained by a computer simulation that assumes the blood flow to be proportional to the intraosseous pressure.

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