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Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1

✍ Scribed by Pan Kee Bae; Jee Hyun Kim; Hae Soo Kim; In Kwon Chung; Sang Gi Paik; Chong-Kyo Lee

Book ID
113457279
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
584 KB
Volume
70
Category
Article
ISSN
0166-3542

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✍ Masayuki Saijo; Tatsuo Suzutani; Masahiro Niikura; Shigeru Morikawa; Ichiro Kura πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 127 KB

## Abstract We previously isolated an acyclovir (ACV)‐resistant herpes simplex virus type 1 (HSV‐1), strain TAR, from a child with Wiskott‐Aldrich syndrome. An acyclovir‐sensitive HSV‐1, strain TAS, had been isolated from the same patient before the isolation of HSV‐1 TAR. The TK protein of ACV‐sen