## Abstract We previously isolated an acyclovir (ACV)βresistant herpes simplex virus type 1 (HSVβ1), strain TAR, from a child with WiskottβAldrich syndrome. An acyclovirβsensitive HSVβ1, strain TAS, had been isolated from the same patient before the isolation of HSVβ1 TAR. The TK protein of ACVβsen
β¦ LIBER β¦
Characterization of Herpes Simplex Virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity
β Scribed by Mark S. Kokoris; Margaret E. Black
- Book ID
- 111753288
- Publisher
- Cold Spring Harbor Laboratory Press
- Year
- 2009
- Tongue
- English
- Weight
- 75 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0961-8368
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Recurrent acyclovir (ACV)-resistant (ACV-r) herpes simplex virus type 1 (HSV-1) infections occurred in a patient with Wiskott-Aldrich syndrome, an X-linked recessive immunodeficiency syndrome composed of three clinical characteristics of immunodeficiency, thrombocytopenia, and an eczematous dermatit
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