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Intracellular Na+modulates large conductance Ca2+-activated K+currents in human umbilical vein endothelial cells

✍ Scribed by Guo Hua Liang; Moon Young Kim; Seonghee Park; Ji Aee Kim; Shinkyu Choi; Suk Hyo Suh


Publisher
Springer
Year
2008
Tongue
English
Weight
361 KB
Volume
457
Category
Article
ISSN
0031-6768

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✍ Sheng-Nan Wu; Hui-Fang Li; Ai-Yu Shen πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 329 KB πŸ‘ 2 views

The effect of pinacidil, an opener of ATP-sensitive K + (K ATP ) channels, on large-conductance Ca 2+ -activated K+ (BK Ca ) channels was investigated in cultured endothelial cells of human umbilical veins. In whole cell configuration, pinacidil (30 Β΅M) increased the amplitude of K + outward current