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Intracellular Gene Transfer in Rats by Tail Vein Injection of Plasmid DNA

✍ Scribed by Tian Zhou; Kenya Kamimura; Guisheng Zhang; Dexi Liu

Book ID
111767684
Publisher
American Association of Pharmaceutical Scientists
Year
2010
Tongue
English
Weight
536 KB
Volume
12
Category
Article
ISSN
1550-7416

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✍ MichΓ¨le Lecocq; Fanjam Andrianaivo; Marie-ThΓ©rΓ¨se Warnier; Simone Wattiaux-De Co πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 218 KB

## Abstract ## Background An efficient gene transfer can be achieved in mouse liver by a rapid tail vein injection of a large volume of plasmid DNA solution (hydrodynamics‐based transfection). The mechanism of gene transfer by this procedure is not known. It must be related to the uptake and intra