Intracellular delivery of protein and peptide therapeutics
โ Scribed by Vladimir Torchilin
- Book ID
- 119226429
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 374 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1740-6749
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In order to probe intracellular signaling based on interactions of thousands of proteins expressed in the living cell, new methods of noninvasive delivery of functional peptides and proteins to cells have been developed. These include cellular import of peptides and proteins based on the cell-membra
The safety and efficacy of protein therapeutics are limited by three interrelated pharmaceutical issues, in vitro and in vivo instability, immunogenicity and shorter half-lives. Novel drug modifications for overcoming these issues are under investigation and include covalent attachment of poly(ethyl