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Intracellular bretylium blocks Na+ and K+ currents in heart cells

✍ Scribed by Ghassan Bkaily; Marcel D. Payet; Mourad Benabderrazik; Rémy Sauvé; Jean-François Renaud; Marvin Bacaner; Nick Sperelakis


Book ID
115881741
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
808 KB
Volume
151
Category
Article
ISSN
0014-2999

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Na+-activated K+current in cardiac cells
✍ H. -N. Luk; E. Carmeliet 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 321 KB

The Na+-activated K + current was studied in inside-out patches and in whole cells isolated from the guinea-pig cardiac ventricle. The single channel conductance showed inward rectification for K § i < K+e , but outward rectification for K +-> K+\_. The open pro-+ i bability was dependent on Na i an