Intrapleural administration of fibrinolytic agents such as urokinase (UK) has been advocated as an alternative method to manage complicated pleural effusion (CPE). Despite the increasing number of empyemas successfully treated with UK in adults, the experience in children is limited to a few cases.
Intracavitary bleomycin in the management of malignant effusions
โ Scribed by William Paladine; Thomas J. Cunningham; Robert Sponzo; Mark Donavan; Kenneth Olson; John Horton
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 367 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0008-543X
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๐ SIMILAR VOLUMES
Ten patients with recurrent pleural effusions due to advanced cancer were treated by intracavitary methylprednisolone acetate (Depo-Medrol [DM], Upjohn, Kalamazoo, MI). They received one to six courses of DM (median, three courses per patient) with doses ranging from 80 to 160 rng per course. Effusi
## BACKGROUND. Treatment of patients with malignant pleural effusions is mostly palliative. Tetracycline and bleomycin are the two most commonly used agents for the treatment of pleurodesis. In this study, the authors used a combination of the two drugs for this particular purpose. ## METHODS.