Although it would appear that there is no difference in outcomes for intraβarterial (IA) versus intravenous cisplatin chemoradiotherapy, one must consider the technique by which the tumors were infused. The authors used the less effective method of bilateral infusion in 58% of patients compared to <
Intra-arterial chemotherapy for head and neck cancer : Is there a verdict?
β Scribed by Coen R. N. Rasch; Michael Hauptmann; Alfons J. M. Balm
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 62 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0008-543X
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During the 10-year period from 1966-1975, 250 patients with various head and neck cancers were treated by intra-arterial chemotherapy using single agents or various combinations. Only 15 patients showed response of I-C category according to Karnofsky's criteria, and 100 patients had I-B response. An
HERE ARE many reports2-8 indicating palli-T ative success in the treatment of inoperable cancers with chemotherapeutic agents administered intra-arterially. They have shown that relief of pain, regression in tumor size, and biopsy evidence of tumor necrosis in the follow-up period can be achieved in
I strated49 5. 7, 10, 11 that protracted intraarterial Chemotherapy with cytotoxic agents is particularly effective in shrinking or causing transient complete regression in cancer. Rest results have been observed in head and neck, limb, and liver cancer, as the specific vascularization of these area
## Abstract ## Background. The purpose of this study was to study the effect of intensive targeted chemoradiation in a group of patients with head and neck cancer with stage IV inoperable disease. ## Methods. We examined 79 patients with inoperable stage IV head and neck cancer receiving intraβa