## Abstract Renewing tissues in the adult organism such as the gastrointestinal (GI) epithelium depend on stem cells for epithelial maintenance and repair. Yet, little is known about the developmental origins of adult stem cells and their niches. Studies of Drosophila adult midgut precursors (AMPs)
Intestinal stem cell asymmetric division in the Drosophila posterior midgut
β Scribed by Steven X. Hou
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 125 KB
- Volume
- 224
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Over the past 2 years, our understanding of intestinal stem cells in the Drosophila posterior midgut has advanced greatly. In this review, I will focus on the establishment of these stem cells in their niche during development and the molecular mechanisms that regulate their asymmetric division in adults. J. Cell. Physiol. 224: 581β584, 2010. Published 2010 WileyβLiss, Inc.
π SIMILAR VOLUMES
## Abstract Previous work has suggested that many stem cells can be found in microanatomic niches, where adjacent somatic cells of the niche control the differentiation and proliferation states of their resident stem cells. Recently published work examining intestinal stem cells (ISCs) in the adult