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Intestinal absorption of drugs II. The effect of inclusion in cyclodextrins on the absorption of dantrolene

โœ Scribed by F. G. J. Poelma; J. J. Tukker; H. W. Hilbers; A. C. A. Jansen


Publisher
Springer Netherlands
Year
1989
Tongue
English
Weight
452 KB
Volume
7
Category
Article
ISSN
0923-0750

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## Abstract A model was developed for predicting the influence of cyclodextrins (CDs) delivered as a physical mixture with drug on oral absorption. CDs are cyclic oligosaccharides which form inclusion complexes with many drugs and are often used as solubilizing agents. The purpose of this work is t