Drug absorption II: Effect of fasting on intestinal drug absorption

✍ Scribed by J. T. Doluisio; G. H. Tan; N. F. Billups; L. Diamond

• Publisher: John Wiley and Sons
• Year: 1969
• Tongue: English
• Weight: 386 KB
• Volume: 58
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600581007

✦ Synopsis

longer periods, the rate of absorption of salicylic acid was found to be much slower (see Fig. 6). This has lead us to study the influence of fasting on drug absorption rates, and the results of that study are to be reported separately (18).

Future publications will deal with the influence of the physicalchemical properties of drugs on their absorption rates from the in situ rat intestine and with correlations between drug transfer kinetics in a three phase in uitro model for drug absorption (11) and drug transfer kinetics in the in situ rat intestinal preparation.