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Interstrand Cross-Link and Bioconjugate Formation in RNA from a Modified Nucleotide

✍ Scribed by Sloane, Jack L.; Greenberg, Marc M.


Book ID
126760136
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
699 KB
Volume
79
Category
Article
ISSN
0022-3263

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## Abstract Studies were performed to determine whether novobiocin can be used to enhance cisplatin (CDDP) cytotoxicity in a human small‐cell lung carcinoma cell line, GLC~4~/CDDP, resistant to CDDP. Continuous incubation with novobiocin enhanced the cytotoxicity of CDDP treatment 1.9‐fold in the p