In order to apply interstitial laser ablation to relatively small liver tumors in humans, it will be necessary to optimize the irradiation schedule. Nd:YAG laser was applied to normal rabbit liver in vivo at various power and energy outputs, including a protocol in which irradiation was repeated twi
Interstitial laser-induced thermotherapy: Influence of carbonization on lesion size
β Scribed by Sturesson, Christian
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 152 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
β¦ Synopsis
Background and Objective:
The size of laser-induced coagulated lesions produced in porcine muscle in vitro using a cylindrical diffusing fiber tip and a conductive heat source, made by covering the diffuser with a hollow steel needle, were compared to investigate the influence of charring. Materials and methods: Light from a Nd: YAG laser was utilized for thermotherapy. A theoretical model for calculating tissue temperature was used to predict the experimental results and to simulate in vivo treatments. Results: The metal-covered tip produced carbonization and tissue vaporization that was not found with the diffuser. After 20 min of irradiation at a laser power of 7 W, the coagulated volumes with and without carbonization were found to be 13.1 cm 3 (range 12.4-14.1 cm 3 , n = 4) and 12.2 cm 3 (range 11.5-13.4 cm 3 , n = 4), respectively. Mathematical simulations showed that in unperfused tissue, a diffusing laser heat source produces smaller lesions than does a conductive heat source at the same power, the difference in coagulated volume becoming smaller with increased treatment time and increased power. Conclusion: Using cylindrical diffusers, interstitial laserinduced thermotherapy without carbonization at the fiber tip can be as efficient as treatment with carbonization. Lasers
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