𝔖 Bobbio Scriptorium
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Interspecies Extrapolation of Toxicity Data

✍ Scribed by Michael J. Goddard; Daniel Krewski


Book ID
109156773
Publisher
Springer
Year
1992
Tongue
English
Weight
338 KB
Volume
12
Category
Article
ISSN
1573-9147

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πŸ“œ SIMILAR VOLUMES


Interspecies extrapolation of pharmacoki
✍ Curtis C. Travis; Robin K. White; Richard C. Ward πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 1020 KB

The purpose of this paper is to use physiologically based pharmacokinetic models to demonstrate that if toxic response is a function of the time profile in physiological time of the concentration of the toxic moiety in the target tissue, then the appropriate interspecies scaling law for toxic compou