The possible acylating effects of cefotaxime on sulfisoxazole binding to serum proteins were evaluated in vitro in samples of human sera incubated with 50-1000 pg ml-l cefotaxime at 37" for 1 h and then dialyzed against saline. This incubation resulted in concentration-related increases in the free
Interpretations of Laboratory Test Data on Serum Protein Binding
✍ Scribed by Norito Takamura; Jin Tokunaga; Kazuhiko Arimori
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract Displacement of cephazolin, a highly protein‐bound β‐lactam antibiotic, by sulpha‐phenazole was studied __in vitro__ and __in vivo. In vitro__, the sulphonamide was effective in displacing the antibiotic from its binding sites at the concentration 100–1000 μmol I^−1^. __In vivo__, both
## Abstract Cardamonin (2′,4′‐dihydroxy‐6′‐methoxychalcone), one of the main constituents from the seeds of __Alpinia katsumadai__ Hayata, belongs to chalcone with its antibacterial, antiinflammatory and other important therapeutic activities of significant potency and low systemic toxicity. In thi
## Abstract Concentrations of disopyramide (D) and mono‐N‐dealkyldisopyramide (MND) were measured in serum and urine following administration of 100, 150, 200, and 300 mg D to four volunteers. The free fraction of D in serum was drug concentration‐dependent in all four subjects following the admini