Interpretation of Oligonucleotide Mass Spectra for Determination of Sequence Using Electrospray Ionization and Tandem Mass Spectrometry
✍ Scribed by Ni, Jinsong; Pomerantz, Steven C.; Rozenski, Jef; Zhang, Yizhou; McCloskey, James A.
- Book ID
- 120644941
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 762 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0003-2700
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Electrospray coupled with tandem mass spectrometry is shown to have utility in determining the molecular mass and the sequence of short modified oligonucleotides. The product ion spectrum of a triply deprotonated molecule precursor is dominated by ions formed via two fragmentation pathw
The collision induced dissociations of oligodeoxynucleotides, 5' and 3'-terminal modified oligodeoxynucleotides and oligophosphorothioates, have been studied by using pneumatically assisted electrospray ionization mass spectrometry on a triple quadrupole instrument. Fragment ions were either produce
## Abstract Diiodothyronines 3,5‐diiodothyronine (3,5‐T2), 3′,5′‐diiodothyronine (3′,5′‐T2), and 3,3′‐diiodothyronine (3,3′‐T2) are important metabolites of 3,5,3′‐triiodothyronine (T3) and 3,3′,5′‐triiodothyronine (rT3; reverse T3). In this paper, a novel and rapid method for identifying and quant