โ Scribed by Pittenger, Paul S.
No coin nor oath required. For personal study only.
Most laboratory men know the behavior of drugs which can be chemically tested and can therefore interpret these results and intelligently apply the assay results to the proper adjustment of the products assayed.
Most of these men, however, have not had sufficient practical experience with Bio-Assays to know the behavior of the various drugs to which the Biologic Assay must be applied.
Therefore, they do not have the necessary experience to properly interpret and apply the results obtained by the assay.
The Biologic Assays themselves can be mastered after limited experience but the proper application and interpretation of the results must be backed by years of experience.
In order to market Biologically standardized preparations which will satisfactorily meet the new U. S. P. Standards, more is required, therefore, than just a working knowledge of the various Biologic Assay methods. This knowledge must be backed by a sufficient amount of practical experience to enable one to properly interpret and apply the information gained from the assay, in issuing instructions for the proper adjustment of the product assayed.
In other words, one should have sufficient experience to know if a certain preparation tests 200?& whether or not it should be diluted 100% and whether a re-assay is necessary after the dilution. Theoretically it should be diluted 100% and a reassay should not be necessary. Practical experience, however, has shown that this is not always the case.
Whether or not a preparation should be given the full theoretical dilution or concentration as based upon the assay depends upon several factors.
Eirst -The pcrrnancncy of the preparation (its rate of deterioration) Second -The percentage over or understrength Thtrd -The age of the preparation at the time of thc assay
๐ SIMILAR VOLUMES
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