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Interphase Detection of BCL6/IgH Fusion Gene in Non-Hodgkin Lymphoma by Fluorescence In Situ Hybridization

✍ Scribed by Yutaka Ueda; Kazuhiro Nishida; Tohru Miki; Shigeo Horiike; Hiroto Kaneko; Syohei Yokota; Shinichi Misawa; Tatsuo Abe; Kei Kashima; Masafumi Taniwaki


Book ID
114136305
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
395 KB
Volume
99
Category
Article
ISSN
0165-4608

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Frequent deletions of 6q23–24 in B-cell
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Deletions of the long arm of chromosome 6 (6q) are among the most frequent chromosome aberrations in malignant lymphomas and often occur as secondary changes in addition to typical translocations, such as t(14;18). Using fluorescence in situ hybridization (FISH) with two YAC probes hybridizing to 6q