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International renal cell cancer study. VII. role of diet

✍ Scribed by Alicja Wolk; Gloria Gridley; Shelley Niwa; Per Lindblad; Margaret McCredie; Anders Mellemgaard; Jack S. Mandel; Jurgen Wahrendorf; Joseph K. McLaughlin; Hans-Olov Adami


Publisher
John Wiley and Sons
Year
1996
Tongue
French
Weight
902 KB
Volume
65
Category
Article
ISSN
0020-7136

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✦ Synopsis


We investigated the role of diet in the etiology of renal cell cancer (RCC) in a multi-center, population-based case-control study conducted in Australia, Denmark, Sweden and the United States, using a shared protocol. A total of 1,185 incident histopathologically confirmed cases (698 men, 487 women) and 1.526 controls (9 I 5 men, 6 I I women) frequency-matched to cases by sex and age were included in the analyses. The association between RCC and diet was estimated by relative risks (RR) and 95% confidence intervals (CI) adjusted for age, sex, study center, body mass index and smoking. A statistically significant positive association was observed for total energy intake (RR = I .7, 95% CI = I .4-2.2 for the highest vs. lowest quartile, p value for trend <O.OOOOl), while the hypothesis that


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