Intermolecular aza-wittig reaction: One-step synthesis of pyrazolo[1,5-a]pyrimidine and imidazo[1,2-b]pyrazole derivatives
β Scribed by Magda A. Barsy; Eman A. El-Rady
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 243 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
Abstract
magnified image
Pyrazolo[1,5βa]pyrimidine and imidazo[1,2βb]pyrazole derivatives were synthesized via intermolecular azaβWittig reaction of 5β(triphenylphosphoranylideneamino)β3βphenylpyrazole 3 derived from 5βaminoβ3βphenylpyrazole with some selected Ξ±βchloroketones.
π SIMILAR VOLUMES
## Abstract magnified image A series of pyrazolopyrimidine and pyrazoloquinozoline derivatives has been synthesized in one step by multicomponent reactions using, 5βaminopyrazole, __pβ__substitutedbenzoylacetonitrile/dimedone and triethylorthoesters. pyrazolopyrimidine derivatives were also studie
Hydrazonoyl bromides 1a-c react with 5-amino-3phenyl-1H-pyrazole, 5-amino-1H-1,2,4-triazole, 2aminopyridine, 2-aminopyrimidine, and 2-aminobenzimidazole to afford the corresponding imidazo[1,2-b]pyrazoles 10, imidazo[1,2-b]-1,2,4-triazoles 11, imidazo[1,2-a]pyridines 16, imidazo[1,2-a]pyrimidines 17