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Intermolecular asymmetric Heck reactions with 2,2-diethyl-2,3-dihydrofuran

โœ Scribed by Alan J Hennessy; David J Connolly; Yvonne M Malone; Patrick J Guiry


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
72 KB
Volume
41
Category
Article
ISSN
0040-4039

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The asymmetric cyclohexenylation of 2,2-
โœ Alan J Hennessy; Yvonne M Malone; Patrick J Guiry ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 154 KB

The palladium catalysed asymmetric cyclohexenylation of 2,2-dimethyl-2,3-dihydrofuran is described. Use of this substrate allowed for an easy and direct comparison of a range of ligands in this reaction. The ligands employed included BINAP and phosphinamines and enantioselectivities of up to 97% wer