𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Intermittent clonazepam treatment prevents anticonvulsant tolerance in mice

✍ Scribed by Yasuhiro Suzuki; James Edge; Takashi Mimaki; Philip D. Walson


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
590 KB
Volume
15
Category
Article
ISSN
0920-1211

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Monoamine turnover in the brain of mice
✍ H.-H Frey; S Jung; R Scherkl πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 689 KB

Mice were treated for 14 days with clonazepam, 0.5 mg/kg i.p. twice daily, during which time partial tolerance to the anticonvulsant effect against pentetrazole developed. The development of tolerance was paralleled by a reduced turnover of noradrenaline in the whole brain, and of dopamine in the mi

Prevention of epilepsy by taurine treatm
✍ F. Junyent; J. Utrera; R. Romero; M. PallΓ s; A. Camins; D. Duque; C. Auladell πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 422 KB

## Abstract An experimental model based on kainic acid (KA) injections replicates many phenomenological features of human temporal lobe epilepsy, the most common type of epilepsy in adults. Taurine, 2‐aminoethanesulfonic acid, present in high concentrations in many invertebrate and vertebrate syste

Leptin treatment prevents type I diabeti
✍ Katherine J. Motyl; Laura R. McCabe πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 281 KB

## Abstract Leptin is a hormone secreted by adipocytes that is implicated in the regulation of bone density. Serum leptin levels are decreased in rodent models of type 1 (T1‐) diabetes and in diabetic patients. Whether leptin mediates diabetic bone changes is unclear. Therefore, we treated control