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Interleukin (IL) 17 activates mitogen-activated protein kinases leading to IL-8 production in gastric epithelial cells

✍ Scribed by Sebkova, Ladislava; Pellicano, Antonia; Monteleone, Giovanni; Grazioli, Barbara; Pugliano, Francesco; Imeneo, Maria G.; Guarnieri, Giovanni; Pallone, Francesco; Luzza, Francesco


Book ID
123451253
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
262 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Inflammatory cytokines are well known to play crucial roles in the pathogenesis of rheumatoid arthritis. Among them, interleukin (IL)‐17 is a cytokine that is mainly synthesized by activated T cells and its receptors are present in osteoblasts. The synthesis of IL‐6, known to stimulate