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Interleukin-6 secretion from the human astrocytoma cell line, U373 MG, induced by substance P

โœ Scribed by B.D. Gitter; D.C. Waters; D. Regoli; A.L. Glasebrook; J.J. Howbert


Book ID
119117637
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
52 KB
Volume
37
Category
Article
ISSN
0167-0115

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Variations in intracellular free calcium concentration (A1Cazfli) were measured in intact and isolated human astrocytoma cells (U373 MG) loaded with fura-2 acetoxymethylester. Microperfusion of 50 nM substance P (SP), applied for 1 s, increased [Ca" ' Ii by 351 nM from a stable basal level of [Ca2+l