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Interleukin-6 receptor superantagonist Sant7 inhibits TGF-β-induced proliferation of human lung fibroblasts

✍ Scribed by L. Gallelli; D. Falcone; G. Pelaia; T. Renda; R. Terracciano; N. Malara; A. Vatrella; A. Sanduzzi; B. D’Agostino; F. Rossi; C. Vancheri; R. Maselli; S. A. Marsico; R. Savino

Book ID: 108677857
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 564 KB
Volume: 41
Category: Article
ISSN: 0960-7722
DOI: 10.1111/j.1365-2184.2008.00538.x

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## Abstract Transforming growth factor‐β1 (TGF‐β1) is crucially involved in the fibrotic events characterizing interstitial lung diseases (ILDs), as well as in the airway remodeling process typical of asthma. Within such a context, the aim of our study was to investigate, in primary cultures of nor