𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of pirfenidone on proliferation, TGF-β-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts

✍ Scribed by Conte, Enrico; Gili, Elisa; Fagone, Evelina; Fruciano, Mary; Iemmolo, Maria; Vancheri, Carlo

Book ID
122294551
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
962 KB
Volume
58
Category
Article
ISSN
0928-0987

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The differential impact of PDE4 subtypes
The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion
✍ Jens Selige; Armin Hatzelmann; Torsten Dunkern 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 745 KB

## Abstract Lung fibroblast proliferation and differentiation into myofibroblasts are pathological key events during development of lung fibrosis. Cyclic nucleotide signaling is described as a negative modulator of these cellular processes, and cyclic nucleotide degrading type 4 phosphodiesterases

Effects of TGF-β and glucocorticoids on
Effects of TGF-β and glucocorticoids on map kinase phosphorylation, IL-6/IL-11 secretion and cell proliferation in primary cultures of human lung fibroblasts
✍ Girolamo Pelaia; Luca Gallelli; Bruno D'Agostino; Alessandro Vatrella; Giovanni 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB 👁 1 views

## Abstract Transforming growth factor‐β1 (TGF‐β1) is crucially involved in the fibrotic events characterizing interstitial lung diseases (ILDs), as well as in the airway remodeling process typical of asthma. Within such a context, the aim of our study was to investigate, in primary cultures of nor