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Interleukin-4 receptor expression by human B cells: Functional analysis with a human interleukin-4 toxin, DAB389IL-4

✍ Scribed by Jabara, Haifa H.; Vercelli, Donata; Schneider, Lynda C.; Williams, Diane P.; Genbauffe, Frank S.; Poisson, Louis R.; Waters, Cory A.; Geha, Raif S.


Book ID
119494849
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
977 KB
Volume
95
Category
Article
ISSN
1097-6825

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## Abstract The growth‐inhibitory effect of interleukin‐4 (IL‐4) was investigated in a panel of 7 human colorectal‐carcinoma cell lines. In 5 cell lines (HT29, WiDr, LS41 IN, LS513, LS1034) a dosedependent reduction of proliferation was documented. At 100 U/ml, IL‐4 inhibited thymidine incorporatio