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Interleukin-3 prevents neuronal death induced by amyloid peptide

✍ Scribed by Angara Zambrano; Carola Otth; Lorena Mujica; Ilona I Concha; Ricardo B Maccioni

Book ID
115007219
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
620 KB
Volume
8
Category
Article
ISSN
1471-2202

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## Abstract Minocycline, a second‐generation tetracycline compound, has been examined as a neuroprotectant in β‐amyloid (Aβ)‐injected rat hippocampus. At 7 days post‐injection, Aβ~1‐42~ caused a significant loss of granule cell layer neurons (28% reduction) compared to control uninjected hippocampu