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Amyloid β-Peptide Inhibits Neuronal Glucose Uptake by Preventing Exocytosis

✍ Scribed by Etsuro Uemura; Heather West Greenlee

Book ID
115607561
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
389 KB
Volume
170
Category
Article
ISSN
0014-4886

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## Abstract Minocycline, a second‐generation tetracycline compound, has been examined as a neuroprotectant in β‐amyloid (Aβ)‐injected rat hippocampus. At 7 days post‐injection, Aβ~1‐42~ caused a significant loss of granule cell layer neurons (28% reduction) compared to control uninjected hippocampu