✦ LIBER ✦

Interleukin-3 modulation of mouse bone marrow derived mast cell receptors for somatostatin

✍ Scribed by F. K. Renold; P. Dazin; E. J. Goetzl; D. G. Payan

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 706 KB
Volume: 18
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490180128

No coin nor oath required. For personal study only.

✦ Synopsis

Receptors for somatostatin (SOW were identified on mouse bone marrow derived mast cells (MBMMC) and shown to vary in expression with the state of proliferation and differentiation of the MBMMC. Flow cytometric studies of the binding of fluoresceinlabeled SOM and concurrent analyses of the binding of ['251]SOM demonstrated that the population of MBMMC capable of recognizing SOM specifically is that exhibiting a proliferative response to interleukin-3. The MBMMC that bound SOM reached a maximal number at 72 hr following the addition of interleukin-3, and were distributed principally in the Gz/M phase of the cell cycle. SOM did not influence directly the proliferative responses of MBMMC to interleukin-3. The level of expression of SOM receptors thus may reflect the state of differentiation of mast cells, as well as determining the functional sensitivity to the inhibitory effects of SOM.

📜 SIMILAR VOLUMES

Preferential expression of interleukin-1

Preferential expression of interleukin-12 or interleukin-4 by murine bone marrow mast cells derived in mast cell growth factor or interleukin-3

✍ Tracey J. Smith; Lori A. Ducharme; John H. Weis 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 584 KB

Characterization of granulocytes and mas

Characterization of granulocytes and mast cells in cultures of mouse bone marrow stimulated with interleukin-3

✍ James G. Bender; Dennis E. Van Epps; Carleton C. Stewart 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 780 KB

Bone marrow cells in liquid culture with interleukin 3 produce a population of non-adherent granulocytes and mast cells. Flow cytometry was used to identify granulocytes and mast cells on the basis of the physical properties of perpendicular light scatter (PLS) and coulter volume (CV) as well as the

Specific high-affinity receptors for int

Specific high-affinity receptors for interferon-γ on mouse bone marrow-derived mast cells: inhibitory effect of interferon-γ on mast cell precursors

✍ Joëlle Nafziger; Michel Arock; Jean-Jacques Guillosson; Juana Wietzerbin 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 492 KB

Polybrene and interleukin-4: two opposin

Polybrene and interleukin-4: two opposing factors for retroviral transduction of bone-marrow-derived dendritic cells

✍ Stéphanie Fresnay; David E. Chalmers; Christophe Ferrand; Christine Colombain; I 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB

## Abstract ## Background Gene transfer using retroviral transduction offers the advantage of long‐term transgene expression in developing strategies that use dendritic cells (DCs) for immunotherapy. The goal of this study was to infect DCs in an immature state in order to take advantage of their

P-selectin glycoprotein ligand-1 mediate

P-selectin glycoprotein ligand-1 mediates rolling of mouse bone marrow-derived mast cells on P-selectin but not efficiently on E-selectin

✍ Martin Steegmaier; James E. Blanks; Eric Borges; Dietmar Vestweber 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 744 KB

Modulation of the epidermal growth facto

Modulation of the epidermal growth factor receptor by brain-derived growth factor in Swiss mouse 3T3 cells

✍ Shuan Shian Huang; Vinata B. Lokeshwar; Jung San Huang 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 721 KB

Incubation of Swiss mouse 3T3 cells at 37°C with bovine brain-derived growth factor (BDGF) decreased the cell surface '251-EGF binding activity of these cells by 70-80%. This down-modulation of the EGF receptor by BDGF was time, temperature, and dose dependent. Scatchard plot analysis indicated that