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Interleukin-28B genetic variations and response to interferon-based therapy: Asian perspectives

✍ Scribed by Chen-Hua Liu; Jia-Horng Kao


Book ID
108954241
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
107 KB
Volume
26
Category
Article
ISSN
0815-9319

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Innate immunity plays an important role in host antiviral response to hepatitis C viral (HCV) infection. Recently, single nucleotide polymorphisms (SNPs) of IL28B and host response to peginterferon a (PEG-IFNa) and ribavirin (RBV) were shown to be strongly associated. We aimed to determine the gene