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Interleukin-2 activated human killer lymphocytes: Lack of involvement of interferon in the development of IL-2-activated killer lymphocytes

✍ Scribed by Nitin K. Damle; Laura V. Doyle

Publisher: John Wiley and Sons
Year: 1987
Tongue: French
Weight: 683 KB
Volume: 40
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910400415

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✦ Synopsis

When cultured with native or recombinant interleukin-2 (IL-2) human small agranular lymphocytes acquire the ability to kill various tumor targets. The development of these IL-2 activated killer (IAK) cells, also known as LAK, is observed in the absence of antigen or mitogen. Interferons are known to 'To whom reprint requests should be sent.

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