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Interleukin-1α Secreted by Pancreatic Cancer Cells Promotes Angiogenesis and Its Therapeutic Implications

✍ Scribed by Yoichi Matsuo; Hirozumi Sawai; Nobuo Ochi; Akira Yasuda; Hiroki Takahashi; Hitoshi Funahashi; Hiromitsu Takeyama; Sushovan Guha


Book ID
116704424
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
937 KB
Volume
153
Category
Article
ISSN
0022-4804

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## Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases. Novel molecularly targeted therapies are urgently needed. Here, we extended our studies on the role of protein kinase D1 (PKD1) in PDAC cell lines. Given that Panc‐1 express moderate levels of PKD1, we used retr