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Cancer Cell-Derived Interleukin-1alpha Promotes HGF Secretion by Stromal Cells and Enhances Metastatic Potential in Colon Cancer Cells

✍ Scribed by Y. Matsuo; H. Takahashi; N. Ochi; K. Tsuboi; H. Funahashi; Y. Okada; H. Takeyama

Book ID: 116707958
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 51 KB
Volume: 172
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2011.11.113

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## Abstract The __nm23‐H1__ gene is known as a potential metastasis suppressor gene in various types of carcinomas. However, the role of __nm23‐H1__ in colorectal carcinoma still remains controversial and the cellular mechanisms by which its protein may modulate the metastatic phenotype are not yet