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Interleukin-1α and tumor necrosis factor-α protect cells against natural killer cell-mediated cytotoxicity and natural killer cytotoxic factor

✍ Scribed by Zvi Reiter; Menachem Rubinstein

Book ID
113134509
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
713 KB
Volume
125
Category
Article
ISSN
0008-8749

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## Abstract Natural killer cell stimulatory factor (NKSF) or interleukin‐12 (IL‐12) is a heterodimeric cytokine with pleiomorphic effects on T and NK cells, including induction of lymphokine production, mitogenesis, and enhancement of spontaneous cytotoxic activity. Similarly to IL‐2, NKSF/IL‐12 en