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Interleukin-12 increases bispecific-antibody-mediated natural killer cell cytotoxicity against human tumors

✍ Scribed by Ugur Sahin; Sylvia Kraft-Bauer; Sascha Ohnesorge; M. Pfreundschuh; Christoph Renner

Book ID
105968085
Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
134 KB
Volume
42
Category
Article
ISSN
0340-7004

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## Abstract Natural killer cell stimulatory factor (NKSF) or interleukin‐12 (IL‐12) is a heterodimeric cytokine with pleiomorphic effects on T and NK cells, including induction of lymphokine production, mitogenesis, and enhancement of spontaneous cytotoxic activity. Similarly to IL‐2, NKSF/IL‐12 en