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Interleukin-18 as a mediator of systemic juvenile idiopathic arthritis

✍ Scribed by Marija Jelušić; Ivan Krešimir Lukić; Lana Tambić-Bukovac; Klara Dubravčić; Ivan Malčić; Igor Rudan; Drago Batinić


Book ID
106264783
Publisher
Springer
Year
2006
Tongue
English
Weight
84 KB
Volume
26
Category
Article
ISSN
0770-3198

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## Abstract The aberrant induction of proinflammatory cytokines is considered to be crucial in the pathogenesis of systemic juvenile idiopathic arthritis and adult‐onset Still's disease. Interleukin‐18 (IL‐18) in particular has been reported to be a candidate for the key cytokine in both diseases;