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Interleukin-17 expression in neutrophils and Th17 cells in cutaneous T-cell lymphoma associated with neutrophilic infiltrate of the skin

✍ Scribed by L. Fontao; N.C. Brembilla; I. Masouyé; G. Kaya; C. Prins; N. Dupin; J.-H. Saurat; C. Chizzolini; V. Piguet

Book ID
108672034
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
420 KB
Volume
166
Category
Article
ISSN
0007-0963

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## Abstract Interleukin‐17 (IL‐17) is a proinflammatory cytokine mainly produced by activated CD4^+^ CD45RO T cells. In mice, we have demonstrated that, depending on the model, IL‐17 may act as a tumor growth‐promoting or ‐inhibiting factor. In order to address the relevance of these models in huma