Although tumor-specific T lymphocytes recognize tumorassociated antigens (TAA) present on their cell surface via major histocompatibility complex (MHC) molecules, T cells require other activating signals. These are provided by costimulatory molecules, including B7-1 (CD80), B7-2 (CD86) and intercell
Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors
โ Scribed by Laurence Zitvogel; Paul D. Robbins; Walter J. Storkus; Martha R. Clarke; Markus J. Maeurer; Ronna L. Campbell; C. Geoffrey Davis; Hideaki Tahara; Robert D. Schreiber; Michael T. Lotze
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 734 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0014-2980
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