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Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis

โœ Scribed by Natalie A Carter, Elizabeth C Rosser, Claudia Mauri


Book ID
120706040
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
361 KB
Volume
14
Category
Article
ISSN
1478-6354

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## Abstract ## Objective To investigate the potential therapeutic action of the immunomodulatory neuropeptide urocortin (UCN) in an experimental model of rheumatoid arthritis (RA). ## Methods After disease onset, DBA/1J mice with collagenโ€induced arthritis (CIA) were treated with UCN, and the in