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Interleukin-10 inhibits endotoxin-induced tissue factor mRNA production by human monocytes

✍ Scribed by M. Ramani; V. Ollivier; F. Khechai; T. Vu; C. Ternisien; F. Bridey; D. de Prost

Book ID: 115928725
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 252 KB
Volume: 334
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(93)81693-t

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Tissue factor (TF) is a glycoprotein which acts as a trigger of the coagulation cascade. TF expression may be induced at the surface of monocytes and endothelial cells by several stimuli including bacterial endotoxin U S ) and cytokines (IL1 p, TNFa) and there is a large body of evidence for the inv