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Interleukin 1 and protein kinase C activator are dissimilar in their effects on Il-2 receptor expression and Il-2 secretion by T lymphocytes

✍ Scribed by Alemseged Truneh; Philip Simon; Anne-Marie Schmitt-Verhulst


Book ID
113133514
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
704 KB
Volume
103
Category
Article
ISSN
0008-8749

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Resting human T lymphocytes do not express receptors for interleukin-2, but expression is rapidly induced by exposure to PHA. After maximal expression 2-3 days after stimulation, a progressive decline in receptor number is observed. Receptor expression can be augmented by reexposure to PHA. In this