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Interleaved 1H and 31P spectroscopic imaging for studying regional brain injury

โœ Scribed by L.-H. Chang; Y. Cohen; P.R. Weinstein; L. Chileuitt; T.L. James


Book ID
103909373
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
771 KB
Volume
9
Category
Article
ISSN
0730-725X

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โœฆ Synopsis


We present a new approach for in vivo localized spectroscopy which combines 1H and 31P one-dimensional spectroscopic imaging pulse sequences in an interleaved, time-shared manner using a surface coil. This approach was used to acquire metabolic information from a rat brain with regional ischemia at 4.7 Tesla. Spectra with very good signal-to-noise ratios, void of chemical shift artifacts, are obtainable from voxel sizes less than 0.3 cm3 in 40 min. Advantages and drawbacks of the proposed methodology are discussed.


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