## Abstract A technique is demonstrated to obtain interleaved proton (^1^H) and ^1^Hโdecoupled phosphorus (^31^P) spectra of human brain using 2D CSI. A modified commercial fullโbody imager and a dualโtuned birdcage headโcoil were employed. Because proton relaxation times are shorter than those of
Interleaved 1H and 31P spectroscopic imaging for studying regional brain injury
โ Scribed by L.-H. Chang; Y. Cohen; P.R. Weinstein; L. Chileuitt; T.L. James
- Book ID
- 103909373
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 771 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0730-725X
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โฆ Synopsis
We present a new approach for in vivo localized spectroscopy which combines 1H and 31P one-dimensional spectroscopic imaging pulse sequences in an interleaved, time-shared manner using a surface coil. This approach was used to acquire metabolic information from a rat brain with regional ischemia at 4.7 Tesla. Spectra with very good signal-to-noise ratios, void of chemical shift artifacts, are obtainable from voxel sizes less than 0.3 cm3 in 40 min. Advantages and drawbacks of the proposed methodology are discussed.
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