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Interim recruitment goals in clinical trials

โœ Scribed by Young Jack Lee


Book ID
115961535
Publisher
Elsevier Science
Year
1983
Weight
792 KB
Volume
36
Category
Article
ISSN
0021-9681

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The interim analyses based on group sequential procedures are not convenient if the response time relative to the patient accrual rate is long. Since in most trials patients are accrued and randomized continuously, the response data from those already randomized will continue to accumulate when a tr