𝔖 Bobbio Scriptorium
✦   LIBER   ✦

INTERFERON-γ AND INTERLEUKIN 4 INHIBIT INTERLEUKIN 1β-INDUCED DELAYED PROSTAGLANDIN E2GENERATION THROUGH SUPPRESSION OF CYCLOOXYGENASE-2 EXPRESSION IN HUMAN FIBROBLASTS

✍ Scribed by Yoshinori Hayashi; Makoto Kobayashi; Hiroshi Kuwata; Gen-ichi Atsumi; Katsutoshi Deguchi; Xiu Feng Wei; Ichiro Kudo; Kohji Hasegawa

Book ID
115596449
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
507 KB
Volume
12
Category
Article
ISSN
1043-4666

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Basic calcium phosphate crystal–induced
Basic calcium phosphate crystal–induced prostaglandin E2 production in human fibroblasts: Role of cyclooxygenase 1, cyclooxygenase 2, and interleukin-1β
✍ Maria P. Morgan; Linda C. Whelan; John D. Sallis; Conor J. McCarthy; Desmond J. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB 👁 2 views

## Abstract ## Objective To elucidate the mechanism of basic calcium phosphate (BCP) crystal–induced prostaglandin E~2~ (PGE~2~) production in human foreskin fibroblasts (HFFs), to identify the signaling pathway involved in the induction of cyclooxygenase 2 (COX‐2) messenger RNA (mRNA) by BCP crys

Inhibition of interleukin-1β–induced cyc
Inhibition of interleukin-1β–induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Δ12,14-prostaglandin J2 through a histone deacetylase–independent mechanism
✍ Katherine Farrajota; Saranette Cheng; Johanne Martel-Pelletier; Hassan Afif; Jea 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 1 views

Objective. The cyclooxygenase (COX) metabolite, 15-deoxy-⌬ 12,14 -prostaglandin J 2 (15d-PGJ 2 ), has been reported to inhibit the expression of a number of genes involved in the pathogenesis of arthritis. However, its effects on COX-2 remain controversial. We undertook this study to investigate the